Araştırma Makalesi
Yıl 2019,
Cilt: 5 Sayı: 3, 186 - 191, 31.12.2019
Öz
Kaynakça
- Albayrak N, Kaya S. Extended spectrum beta lactamases production and antimicrobial resistance ratio of Escherichia coli and Klebsiella pneumoniae strains isolated from various clinical samples. Turk Mikrobiyol Cem Derg. 2009; 39(1-2):16-21.
- Al-salamy AK. Detection of extended spectrum-beta lactamase enzymes producing E. coli that isolated from urine. Kufa Journal for Veterinary Medical Sciences 2012; 3(1):55-66.
- Ayatollahi J, Shahcheraghi SH, Akhondi R, Soluti S. Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd. Iran J Ped Hematol Oncol. 2013; 3(2):78–82.
- Ayub M, Amir JS, Firdous K. E. coli the Most Prevalent Causative Agent Urinary Tract Infection in Pregnancy: Comparative Analysis of Susceptibility and Resistance Pattern of Antimicrobials. Arch Clin Microbiol. 2016; 7:4. doi:10.4172/1989-8436.100054.
- Cappuccino JG, Sherman N. Microbiology: A Laboratory Manual. 7th Edn. Pearson Education (Singapore) 2004, Indian Branch, New Delhi, ISBN: 080532836X. pp: 544.
- Cheema, UK, Saleem S, Chaudary MA. Isolation and Antimicrobial Susceptibility Profile of Microorganisms Isolated from Ventilator Associated Pneumonia Patients. J Infec Dis Treat 2018; 4(1):3. doi:10.21767/2472-1093.100041
- Dash M, Padhi S, Mohanty I, Panda P, Parida B. Antimicrobial resistance in pathogens causing urinary tract infections in a rural community of Odisha, India J Family Community Med. 2013; 20(1):20-6.
- Devrim F, Serdaroğlu E, Çağlar İ, Oruç Y, Demiray N, Bayram N, et al. The emerging resistance in nosocomial urinary tract infections: From the pediatrics perspective. Mediterr J Hematol Infect Dis 2018; 10:1-5.
- Eryilmaz M, Bozkurt ME, Yildiz MM, Akın A. Investigation of the prevalance of extended spectrum beta lactamase producing Escherichia coli strains isolated from various clinical samples. Marmara Ecza Derg 2010; 14:10-12.
- Fajfr M, Louda M, Paterova P, Ryskova L, Pakovsky J, Kosina J. The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study. BMC Urol. 2017; 17:33.
- Fernando MMPSC, Luke WANV, Miththinda JKND, Wickramasinghe RDSS, Sebastiampillai BS, Gunathilake MPML, Silva Premaratna R. Extended spectrum beta lactamase producing organisms causing urinary tract infections in Sri Lanka and their antibiotic susceptibility pattern –A hospital based cross sectional study. BMC Infectious Diseases 2017; 17(1):1.
- Ghafur A, Ramasamy P, Sarathy N, Krishnamurthy R, Durairajan S. Sensitivity pattern of Gram-negative bacteria to the new β-lactam/ β-lactamase inhibitor combination: Cefepime/tazobactam. J Microbiol Infect Dis. 2012; 2(1):5–8.
- Guducuoglu H, Baykal S, Izci H, Berktaş M. Antimicrobial resistance of Escherichia coli and Klebsiella pneumoniae strains that produce extended spectrum beta lactamase. ANKEM Derg 2007; 21(3):155-60.
- Guneysel O, Onur O, Erdede M, Denizbasi A. Trimethoprim/sulfamethoxazole resistance in urinary tract infections. J Emerg Med. 2009; 36:338-41. doi: 10.1016/j.
- Gupta V, Rani H, Singla N, Kaisha N, Chander J. Determination of extended-spectrum- β-Lactamases and AmpC production in uropathogenic isolates of Escherichia coli and susceptibility to Fosfomycin. Lab Physicians. 2013; 5(2):90-3.
- Jones RN, Jenkins SG, Hoban DJ, Pfaller MA, Ramphal R. In vitro efficacy of six cephalosporins tested against Enterobacteriaceae isolated at 38 North American medical centres participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998. Int. J. Antimicrob. Agents., 2000; 15: 111-118.
- Hammerum AM, Heuer Ole E. Human Health Hazards from Antimicrobial-Resistant Escherichia coli of Animal Origin, Clinical Infectious Diseases 2009; 48(7): 916–921.
- Hawser SP, Bouchillon SK, Lascols C, Hackel M, Hoban DJ, Badal RE, Cantón R. Susceptibility of European Escherichia coli clinical isolates from intra-abdominal infections, extended-spectrum β-lactamase occurrence, resistance distribution, and molecular characterization of ertapenem-resistant isolates (SMART 2008-2009). Clin Microbiol Infect. 2012; 18(3):253-9.
- Kang CI, Wi YM, Lee MY, Ko KS, Chung DR, Peck KR. Epidemiology and risk factors of community onset infections caused by extended-spectrum beta-lactamase-producing Escherichia coli strains. J ClinMicrobiol 2012; 50:312–7.
- Karlowsky JA. Trends in antimicrobial resistance among urinary tract infection isolates of Escherichia coli from female outpatients in the United States. Antimicrob Agents Chemother 2002; 46(8):2540–5.
- Lawhale MA, Naikwade R. Recent pattern of drug sensitivity of most commonly isolated uropathogens from Central India. Int J ResMed Sci 2017; 5:3631-6.
- Ling TK, Tam PC, Liu ZK, Cheng AF. Evaluation of VITEK 2 rapid identification and susceptibility testing system against gram-negative clinical isolates. J. Clin. Microbiol. 2001; 39: 2964-6.
- Park YS, Adams-Haduch JM, Shutt KA, et al. Clinical and microbiologic characteristics of cephalosporin-resistant Escherichia coli at three centers in the United States. Antimicrob Agents Chemother. 2012;56(4):1870–1876. doi:10.1128/AAC.05650-11
- Malhotra R, Sikka R, Chaudhary U. Antimicrobial sensitivity pattern among clinical isolates of Escherichia coli in tertiary care centre of Northern India. Int J Res Med Sci 2016; 4:639-42.
- Matyar F, Kaya A, Dinçer S. Antibacterial agents and heavy metal resistance in Gram-negative bacteria isolated from seawater, shrimp and sediment in Iskenderun Bay, Turkey. Science Total and Environment 2000; 407: 279-285.
- Mulla S, Charan J, Panvala T. Antibiotic sensitivity of Enterobacteriaceae at a tertiary care center in India. Chron Young Sci 2011; 2:214-8.
- Mumcuoglu I. Investigation of extended spectrum beta-lactamase production and antimicrobial resistance in Escherichia, Klebsiella and Proteus strains. ANKEM Derg 2004; 18(1):9-11.
- Naber GK, Schaeffer AJ, Heyns CF. Urogenital infections. Ed. 2010. European Association of Urology. –International Consultation on Urological Diseases.
- Niranjan V, Malini A. Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among inpatients. Indian J Med Res. 2014; 139(6): 945–948.
- Rugini CL, Sobottka AM, Fuentefria DB (2015) Occurrence and sensitivity profile of extended spectrum beta-lactamase-producing Enterobacteriaceae at a tertiary hospital in Southern Brazil. Rev. Soc. Bras. Med. Trop. doi: 10.1590/0037-8682-0211-2015. Sah SK, Regmi S, Upreti AR, Pathak S. Antibiotic resistance patterns and evaluation of treatment in out-patients with urinary tract infections in Nepal. Int J Pharm Sci Res 2016; 7(11): 4626-31.
- Sherley M, Gordon DM, Collignon PJ. Evolution of multi-resistance plasmids in Australian clinical isolates of Escherichia coli. Microbiology 2004; 150: 1539-1546.
- Sorlózano A, Gutiérrez J, Piédrola G, Soto MJ. Acceptable performance of VITEK 2 system to detect extended-spectrum beta-lactamases in clinical isolates of Escherichia coli: a comparative study of phenotypic commercial methods and NCCLS guidelines. Diagn Microbiol Infect Dis 2005;51:191-3.
- Tasleem S, Sana S, Syed BN. Sensitivity Pattern of Staphylococcus aureus and Escherichia coli Against Cefaclor and Cefixime. CPQ Medicine 2018; 5(2), 1-6.
- Tadesse DA, Zhao S, Tong, E, Ayers S, Singh A, Bartholomew MJ. Antimicrobial Drug Resistance in Escherichia coli from Humans and Food Animals, United States, 1950–2002. Emerg Infect Dis. 2012; 18(5):741-749. https://dx.doi.org/10.3201/eid1805.111153.
- Ugwu MC, Edeani GI, Ejikeugwu CP, Okezie U, Ejiofor SO. Antibiotic Susceptibility Profile of Escherichia coli and Salmonella Causing Childhood Diarrhoea in Awka Municipality, South-eastern Nigeria. Clin Microbiol 2017; 6: 277. doi:10.4172/2327-5073.1000277.
- Ouzdi ZA, Lamiae Arsalane, Youssef El kamouni, Said Zouhair. The Resistance of Uropathogenic Bacteria to Fosfomycin. Pathology and Laboratory Medicine. 2018; 2(2): 47-50.
- Wagle S, Khanal BR, Tiwari BR. High Susceptibility of Fosfomycin to Uropathogenic Escherichia coli Isolated at Tertiary Care Hospital of Nepal. JAMB 2018; 13(2): 1-8.
- Weissman SJ, Hansen NI, Zaterka-Baxter K, Higgins RD, Stoll BJ. Emergence of Antibiotic Resistance-Associated Clones Among Escherichia coli Recovered from Newborns With Early-Onset Sepsis and Meningitis in the United States, 2008–2009. Journal of the Pediatric Infectious Diseases Society, 2016; 5(3):269–76
Antimicrobial Susceptibility Profiles and Prevalence of ESBLS among Escherichia coli Isolates Recovered from Clinical Specimens in Different Services
Öz
Objective: A
retrospective analysis of the widely used antibiotics all susceptibility
testing results from Escherichia coli cultured from clinical specimens private
hospital from (January 2016 to November 2018) was performed.
Methods: The
VITEK 2 Compact automated microbiology system is designed for automated rapid
antimicrobial susceptibility testing and identification of clinically relevant
bacteria. Minimum inhibitory concentration (MIC) results previously obtained in
recent clinical isolates with well-defined in isolates with well-characterized
resistance mechanisms with the microdilution method were re-interpreted for the
susceptible, intermediate and resistant categories using the 2018 EUCAST
breakpoints. Clinical samples are most commonly isolated from blood, sputum and
urine samples.
Results:
Escherichia coli isolates were highly resistant to ampicillin, cefuroxime and
cefixime 79,16%, 60,41% and 58,33% respectively. Resistance rate of ceftriaxon
was showed in 52,08%. When we compared to resistance of
trimethoprim/sulfamethoxazole, Escherichia coli isolates showed 51,04%
resistance rate. When it comes to the most sensitive antibiotics, sensitivity
rate of fosfomycin, nitrofurantoin, ertapenem, imipenem, meropenem, gentamicin,
and amikacin were 89,58%; 91,66%; 93,75%; 93,75%; 94,79%; 83,33%; 84,37%
respectively.
Conclusion:
Considering the antibiogram, fosfomycin, nitrofurantoin, ertapenem, imipenem,
meropenem, gentamicin and amikacin should be preferred drugs for E. coli
infection isolated from clinical samples.
Anahtar Kelimeler
Kaynakça
- Albayrak N, Kaya S. Extended spectrum beta lactamases production and antimicrobial resistance ratio of Escherichia coli and Klebsiella pneumoniae strains isolated from various clinical samples. Turk Mikrobiyol Cem Derg. 2009; 39(1-2):16-21.
- Al-salamy AK. Detection of extended spectrum-beta lactamase enzymes producing E. coli that isolated from urine. Kufa Journal for Veterinary Medical Sciences 2012; 3(1):55-66.
- Ayatollahi J, Shahcheraghi SH, Akhondi R, Soluti S. Antibiotic Resistance Patterns of Escherichia coli Isolated from Children in Shahid Sadoughi Hospital of Yazd. Iran J Ped Hematol Oncol. 2013; 3(2):78–82.
- Ayub M, Amir JS, Firdous K. E. coli the Most Prevalent Causative Agent Urinary Tract Infection in Pregnancy: Comparative Analysis of Susceptibility and Resistance Pattern of Antimicrobials. Arch Clin Microbiol. 2016; 7:4. doi:10.4172/1989-8436.100054.
- Cappuccino JG, Sherman N. Microbiology: A Laboratory Manual. 7th Edn. Pearson Education (Singapore) 2004, Indian Branch, New Delhi, ISBN: 080532836X. pp: 544.
- Cheema, UK, Saleem S, Chaudary MA. Isolation and Antimicrobial Susceptibility Profile of Microorganisms Isolated from Ventilator Associated Pneumonia Patients. J Infec Dis Treat 2018; 4(1):3. doi:10.21767/2472-1093.100041
- Dash M, Padhi S, Mohanty I, Panda P, Parida B. Antimicrobial resistance in pathogens causing urinary tract infections in a rural community of Odisha, India J Family Community Med. 2013; 20(1):20-6.
- Devrim F, Serdaroğlu E, Çağlar İ, Oruç Y, Demiray N, Bayram N, et al. The emerging resistance in nosocomial urinary tract infections: From the pediatrics perspective. Mediterr J Hematol Infect Dis 2018; 10:1-5.
- Eryilmaz M, Bozkurt ME, Yildiz MM, Akın A. Investigation of the prevalance of extended spectrum beta lactamase producing Escherichia coli strains isolated from various clinical samples. Marmara Ecza Derg 2010; 14:10-12.
- Fajfr M, Louda M, Paterova P, Ryskova L, Pakovsky J, Kosina J. The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study. BMC Urol. 2017; 17:33.
- Fernando MMPSC, Luke WANV, Miththinda JKND, Wickramasinghe RDSS, Sebastiampillai BS, Gunathilake MPML, Silva Premaratna R. Extended spectrum beta lactamase producing organisms causing urinary tract infections in Sri Lanka and their antibiotic susceptibility pattern –A hospital based cross sectional study. BMC Infectious Diseases 2017; 17(1):1.
- Ghafur A, Ramasamy P, Sarathy N, Krishnamurthy R, Durairajan S. Sensitivity pattern of Gram-negative bacteria to the new β-lactam/ β-lactamase inhibitor combination: Cefepime/tazobactam. J Microbiol Infect Dis. 2012; 2(1):5–8.
- Guducuoglu H, Baykal S, Izci H, Berktaş M. Antimicrobial resistance of Escherichia coli and Klebsiella pneumoniae strains that produce extended spectrum beta lactamase. ANKEM Derg 2007; 21(3):155-60.
- Guneysel O, Onur O, Erdede M, Denizbasi A. Trimethoprim/sulfamethoxazole resistance in urinary tract infections. J Emerg Med. 2009; 36:338-41. doi: 10.1016/j.
- Gupta V, Rani H, Singla N, Kaisha N, Chander J. Determination of extended-spectrum- β-Lactamases and AmpC production in uropathogenic isolates of Escherichia coli and susceptibility to Fosfomycin. Lab Physicians. 2013; 5(2):90-3.
- Jones RN, Jenkins SG, Hoban DJ, Pfaller MA, Ramphal R. In vitro efficacy of six cephalosporins tested against Enterobacteriaceae isolated at 38 North American medical centres participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998. Int. J. Antimicrob. Agents., 2000; 15: 111-118.
- Hammerum AM, Heuer Ole E. Human Health Hazards from Antimicrobial-Resistant Escherichia coli of Animal Origin, Clinical Infectious Diseases 2009; 48(7): 916–921.
- Hawser SP, Bouchillon SK, Lascols C, Hackel M, Hoban DJ, Badal RE, Cantón R. Susceptibility of European Escherichia coli clinical isolates from intra-abdominal infections, extended-spectrum β-lactamase occurrence, resistance distribution, and molecular characterization of ertapenem-resistant isolates (SMART 2008-2009). Clin Microbiol Infect. 2012; 18(3):253-9.
- Kang CI, Wi YM, Lee MY, Ko KS, Chung DR, Peck KR. Epidemiology and risk factors of community onset infections caused by extended-spectrum beta-lactamase-producing Escherichia coli strains. J ClinMicrobiol 2012; 50:312–7.
- Karlowsky JA. Trends in antimicrobial resistance among urinary tract infection isolates of Escherichia coli from female outpatients in the United States. Antimicrob Agents Chemother 2002; 46(8):2540–5.
- Lawhale MA, Naikwade R. Recent pattern of drug sensitivity of most commonly isolated uropathogens from Central India. Int J ResMed Sci 2017; 5:3631-6.
- Ling TK, Tam PC, Liu ZK, Cheng AF. Evaluation of VITEK 2 rapid identification and susceptibility testing system against gram-negative clinical isolates. J. Clin. Microbiol. 2001; 39: 2964-6.
- Park YS, Adams-Haduch JM, Shutt KA, et al. Clinical and microbiologic characteristics of cephalosporin-resistant Escherichia coli at three centers in the United States. Antimicrob Agents Chemother. 2012;56(4):1870–1876. doi:10.1128/AAC.05650-11
- Malhotra R, Sikka R, Chaudhary U. Antimicrobial sensitivity pattern among clinical isolates of Escherichia coli in tertiary care centre of Northern India. Int J Res Med Sci 2016; 4:639-42.
- Matyar F, Kaya A, Dinçer S. Antibacterial agents and heavy metal resistance in Gram-negative bacteria isolated from seawater, shrimp and sediment in Iskenderun Bay, Turkey. Science Total and Environment 2000; 407: 279-285.
- Mulla S, Charan J, Panvala T. Antibiotic sensitivity of Enterobacteriaceae at a tertiary care center in India. Chron Young Sci 2011; 2:214-8.
- Mumcuoglu I. Investigation of extended spectrum beta-lactamase production and antimicrobial resistance in Escherichia, Klebsiella and Proteus strains. ANKEM Derg 2004; 18(1):9-11.
- Naber GK, Schaeffer AJ, Heyns CF. Urogenital infections. Ed. 2010. European Association of Urology. –International Consultation on Urological Diseases.
- Niranjan V, Malini A. Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among inpatients. Indian J Med Res. 2014; 139(6): 945–948.
- Rugini CL, Sobottka AM, Fuentefria DB (2015) Occurrence and sensitivity profile of extended spectrum beta-lactamase-producing Enterobacteriaceae at a tertiary hospital in Southern Brazil. Rev. Soc. Bras. Med. Trop. doi: 10.1590/0037-8682-0211-2015. Sah SK, Regmi S, Upreti AR, Pathak S. Antibiotic resistance patterns and evaluation of treatment in out-patients with urinary tract infections in Nepal. Int J Pharm Sci Res 2016; 7(11): 4626-31.
- Sherley M, Gordon DM, Collignon PJ. Evolution of multi-resistance plasmids in Australian clinical isolates of Escherichia coli. Microbiology 2004; 150: 1539-1546.
- Sorlózano A, Gutiérrez J, Piédrola G, Soto MJ. Acceptable performance of VITEK 2 system to detect extended-spectrum beta-lactamases in clinical isolates of Escherichia coli: a comparative study of phenotypic commercial methods and NCCLS guidelines. Diagn Microbiol Infect Dis 2005;51:191-3.
- Tasleem S, Sana S, Syed BN. Sensitivity Pattern of Staphylococcus aureus and Escherichia coli Against Cefaclor and Cefixime. CPQ Medicine 2018; 5(2), 1-6.
- Tadesse DA, Zhao S, Tong, E, Ayers S, Singh A, Bartholomew MJ. Antimicrobial Drug Resistance in Escherichia coli from Humans and Food Animals, United States, 1950–2002. Emerg Infect Dis. 2012; 18(5):741-749. https://dx.doi.org/10.3201/eid1805.111153.
- Ugwu MC, Edeani GI, Ejikeugwu CP, Okezie U, Ejiofor SO. Antibiotic Susceptibility Profile of Escherichia coli and Salmonella Causing Childhood Diarrhoea in Awka Municipality, South-eastern Nigeria. Clin Microbiol 2017; 6: 277. doi:10.4172/2327-5073.1000277.
- Ouzdi ZA, Lamiae Arsalane, Youssef El kamouni, Said Zouhair. The Resistance of Uropathogenic Bacteria to Fosfomycin. Pathology and Laboratory Medicine. 2018; 2(2): 47-50.
- Wagle S, Khanal BR, Tiwari BR. High Susceptibility of Fosfomycin to Uropathogenic Escherichia coli Isolated at Tertiary Care Hospital of Nepal. JAMB 2018; 13(2): 1-8.
- Weissman SJ, Hansen NI, Zaterka-Baxter K, Higgins RD, Stoll BJ. Emergence of Antibiotic Resistance-Associated Clones Among Escherichia coli Recovered from Newborns With Early-Onset Sepsis and Meningitis in the United States, 2008–2009. Journal of the Pediatric Infectious Diseases Society, 2016; 5(3):269–76
Toplam 38 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Araştırma Makaleleri |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2019 |
| Yayımlandığı Sayı | Yıl 2019 Cilt: 5 Sayı: 3 |
